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目的观察愈疡汤联合美沙拉嗪治疗湿热内蕴型溃疡性结肠炎的临床疗效。方法按照就诊顺序将136例患者随机分为两组,其中治疗组69例,对照组67例。治疗组给予愈疡汤减灌肠联合美沙拉嗪肠溶片口服,对照组予美沙拉嗪肠溶片口服,观察四个疗程。结果治疗组总有效率为95.6%,对照组为85.1%,两组疗效比较,治疗组明显优于对照组,差异有统计学意义(P<0.05)。治疗组的症状积分及结肠镜下结肠黏膜积分均比对照组降低(P<0.05)。结论中药愈疡汤加减联合西药美沙拉嗪肠溶片口服对湿热内蕴型-溃疡性结肠炎的临床疗效肯定,值得临床推广。
Objective To observe the clinical efficacy of Yuyang Decoction combined with mesalazine in the treatment of damp-heat intrinsic ulcerative colitis. Methods According to the order of treatment, 136 patients were randomly divided into two groups, of which 69 cases in the treatment group and 67 cases in the control group. The treatment group was given Yuyang Decoction combined with mesalazine enteric-coated tablets orally, and the control group was given mesalazine enteric-coated tablets orally, and the four courses of treatment were observed. Results The total effective rate was 95.6% in the treatment group and 85.1% in the control group. The curative effect of the two groups was obviously superior to that of the control group (P <0.05). Symptom scores and colonic mucosal scores in the treatment group were lower than those in the control group (P <0.05). Conclusion Chinese medicine Yuyang Decoction combined with western medicine Mesalazine enteric-coated tablets on the clinical efficacy of damp-heat intrinsic ulcerative colitis certainly worthy of clinical promotion.