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目的 :探讨肾小球轻微病变 NS并发 IARF的病理特征、治疗效果及预后。方法 :回顾性分析 12例肾小球轻微病变 NS并发 IARF患者的临床特征、病理结果、治疗及预后情况。结果 :本组 12例病理示肾小球病变轻微 ,肾小管间质病变较广泛。 10例肾功能恢复正常、2例好转 ,肾衰恢复或好转的平均时间为 2 2 .4± 15.3d;8例 NS缓解 ,时间为 4 0 .5± 2 0 .7d。结论 :肾小球轻微病变 NS并发 IARF可能为肾小管间质的亚致死性损伤所致 ,兼顾 PNS和 ARF两个环节的治疗 ,预后良好。
Objective: To investigate the pathological features, therapeutic effect and prognosis of NSA complicated with mild glomerular lesions. Methods: The clinical features, pathological findings, treatment and prognosis of 12 patients with mild glomerular lesions complicated with IARF were retrospectively analyzed. Results: The group of 12 cases of pathological glomerular lesions showed mild tubulointerstitial lesions more extensive. 10 cases of normal renal function returned to normal, 2 cases improved, the average recovery or improvement of renal failure was 22.4 ± 15.3d; 8 cases of NS ease, the time was 40.5 ± 20.7d. CONCLUSIONS: NS complicated with IARF in patients with mild glomerular lesions may be caused by sublethal injury of tubulointerstitial stroma. Both PNS and ARF should be taken into account and the prognosis is good.