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一、概述缓慢进展的失语最早于１８世纪由Ｐｉｃｋ以及Ｒｏｓｅｎｆｅｌｄ先后描述，病人常表现为命名障碍的语言障碍，常见于Ａｌｚｈｅｉｍｅｒ病（ＡＤ）、Ｐｉｃｋ病（ＰｉＤ）［１］。１９８２年Ｍｅｓｕｌａｍ［２］报道６例缓慢进展的失语病人，无智能和行为障碍，并首
First, an overview of the slow aphasia was first described by Pick and Rosenfeld in the eighteenth century. Patients often manifest as verbal disturbances of naming disorder, common in Alzheimer’s disease (AD) and Pick’s disease (PiD) [1]. In 1982, Mesulam [2] reported 6 cases of slow-progress aphasia without intellectual and behavioral disorders, and the first