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1973年Shepherd等证实慢性肾功能衰竭常併发十二指肠溃疡,并有显著夜间和基础胃液过度分泌。本文旨在研究其病理生理基础及各种治疗方法的效果。作者对4例男性慢性肾功能衰竭的病人进行研究,其中2例为慢性肾小球肾炎;1例为慢性肾盂肾炎;1例为未能分类的慢性肾病。实验结果发现,慢性肾功能衰竭发生十二指肠溃疡可能与十二指肠内酸浓度异常增高有关。病人胃液过度分泌,胃及十二指肠液低pH值和酸度增高,这不但加剧了十二指肠的损伤,而且影响胰腺对酸的反应。本文2例胆道口壶腹部pH值很低,而在正常
Shepherd 1973 confirmed that chronic renal failure often complicated by duodenal ulcers, and there is a significant overnight and basal gastric juice over-secretion. This article aims to study its pathophysiology and the effects of various treatment methods. The authors studied four patients with chronic renal failure in men, of which two were chronic glomerulonephritis; one was chronic pyelonephritis; one was chronic kidney disease that failed to be classified. The experimental results showed that duodenal ulcer in chronic renal failure may be related to the abnormal increase of intraduodenal acid concentration. Patients with excessive secretion of gastric juice, stomach and duodenal fluid low pH and increased acidity, which not only exacerbated the duodenal injury, but also affect the pancreatic response to acid. This article 2 cases of gallbladder ampulla pH value is low, but normal