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血浆中非结合胆红素浓度超过0.8毫克％者为非结合胆红素性黄疸,可以是单纯非结合胆红素升高,也可以同时伴有结合胆红素升高。能引起非结合胆红素升高的原因很多,但它们具有以下共同特点:(1)单纯性非结合胆红素升高时,不发生胆红素尿,因非结合胆红素不溶于水,不能随尿排出。(2)虽有黄疸,但无肝细胞功能不全。(3)新生儿的非结合胆红素若超过15～18毫克％,则可并发胆红素性脑病,即核黄疸。这是由于脂溶性非结合胆红素能透入脑组织、特别是中央基底神经节的缘故。
Plasma concentrations of unconjugated bilirubin more than 0.8 mg% of non-conjugated bilirubin jaundice, can be simply unconjugated bilirubin, can also be accompanied by elevated bilirubin. Can lead to unconjugated bilirubin rise for many reasons, but they share the following characteristics: (1) simple non-conjugated bilirubin, does not occur bilirubin, non-conjugated bilirubin insoluble in water , Can not be discharged with the urine. (2) Although jaundice, but no liver cell dysfunction. (3) neonatal unconjugated bilirubin if more than 15 to 18 mg%, you can complicated with bilirubin encephalopathy, that is, nuclear jaundice. This is due to the fact that fat-soluble, unconjugated bilirubin penetrates into brain tissue, especially the central basal ganglia.