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目的：了解豚鼠内淋巴囊表面的脉管及其粘膜下层结构对内耳功能的影响。方法：用碳素墨水加０．１ｍｏｌ·Ｌ－１甲醛进行左心室灌注，将豚鼠的颞骨标本用冬青油透明并进行显微检查及透射电镜检查。结果：内淋巴囊表面有非常丰富的血管网，而且与乙状窦有很密切的联系。内淋巴囊周围被毛细血管、微静脉、静脉和个别微动脉形成的一个细密的环状血管网所包绕。毛细血管周围有丰富的淋巴窦。毛细血管与淋巴窦构成一个完整、细密的网状结构。结论：内淋巴囊不仅是代谢非常活跃的器官，而且粘膜下丰富的淋巴窦与血管网可缓解压力变化对内淋巴造成的影响，借此来维持内淋巴的内环境稳定。提示梅尼埃病可能就是各种原因引起内淋巴囊血液循环障碍，使内淋巴囊的物质交换功能障碍，从而产生内淋巴积水
OBJECTIVE: To investigate the effects of vasculature and submucosal structure on the inner ear of guinea pig endolymphatic sac. METHODS: Left ventricular perfusion was performed with carbon ink plus 0.1 mol·L-1 formaldehyde. The temporal bone samples of guinea pigs were made transparent with wintergreen oil and examined by microscopy and transmission electron microscopy. Results: The endolymphatic sac surface has a very rich vascular network, and with the sigmoid sinus are closely linked. Around the endolymphatic sac surrounded by capillaries, venules, veins and individual micro-artery formed by a close loop vascular network. Around the capillaries are rich in lymph. Capillary and lymphatic sinus constitute a complete, detailed mesh structure. CONCLUSION: The endolymphatic sac is not only an organ that is metabolically active, but also the submucosal lymphoid sinus and vascular network can relieve the effect of pressure changes on the endolymph and thus maintain the internal environment of the endolymph. Tip Meniere’s disease may be caused by a variety of reasons, endolymphatic sac blood circulation disorders, so that the endolymphatic sac material exchange dysfunction, resulting in endolymphatic hydrops