阿奇霉素联合低剂量茶碱、吸入激素在哮喘治疗中的疗效研究

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目的分析研究阿奇霉素联合低剂量茶碱、吸入激素在哮喘治疗中的临床疗效。方法将84例哮喘患者随机分成治疗组和对照组各42例,治疗组采用阿奇霉素联合低剂量茶碱和吸入激素治疗,对照组采用低剂量茶碱联合吸入激素治疗,观察记录两组患者的临床疗效和肺功能改变情况。结果用药1个疗程后,治疗组总有效率明显高于对照组,两组比较差异有统计学意义(P<0.05);两组治疗后肺功能指标均较用药前明显改善,两组比较差异有统计学意义(P<0.05),两组在治疗期间均未出现严重不良反应。结论阿奇霉素联合低剂量茶碱、吸入激素可显著提高哮喘患者的临床疗效,迅速缓解患者症状,且安全性高,值得在临床哮喘治疗中推广使用。 Objective To analyze the clinical efficacy of azithromycin combined with low-dose theophylline and inhaled hormones in the treatment of asthma. Methods Eighty-four patients with asthma were randomly divided into treatment group (n = 42) and control group (n = 42). The treatment group was treated with azithromycin combined with low-dose theophylline and inhaled hormone. The control group was treated with low-dose theophylline combined with inhaled hormone. Efficacy and changes in lung function. Results After one course of treatment, the total effective rate of the treatment group was significantly higher than that of the control group, the difference between the two groups was statistically significant (P <0.05); lung function indexes of both groups were significantly improved after treatment, There was statistical significance (P <0.05), both groups did not appear in the treatment of serious adverse reactions. Conclusion Azithromycin combined with low dose of theophylline and inhaled hormones can significantly improve the clinical efficacy of asthma patients and quickly relieve the symptoms of patients and is safe and worthy of promotion in clinical asthma treatment.
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