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通过一维1HNMR ,13CNMR和二维ROESYNMR技术对盐酸普鲁卡因与β 环糊精(β CD)的相互作用进行了研究 .实验结果表明 ,盐酸普鲁卡因和β CD形成了 1∶1的包结配合物 ,并根据这些数据提出了包结配合物的空间构型 .
The interaction between procaine hydrochloride and β-cyclodextrin (βCD) was studied by one-dimensional 1HNMR, 13CNMR and two-dimensional ROESYNMR.The experimental results showed that procaine hydrochloride and βCD formed a 1: 1 Based on these data, the space configuration of inclusion complex was proposed.