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用异种受精系统分析对照组人精子染色体时,发现其染色体结构畸变率高(6.2%~13.0%),这些畸变可能是人为造成的。因为,应用同种受精技术分析其他物种的精子时,其畸变率低,中国仓鼠精子的畸变率为1.3%,小鼠为0.6%。而且,在人类自然流产者中,其染色体结构畸变率也远远少于数目畸变率(94%的畸变为数目畸变,仅有3~6%是结构畸变,而且仅有一半被认为是新发生的重排)。然而,精子染色体畸变率在个体间的差异和在同一个体内相对时间的稳定性以及使用已知的诱变剂后,畸变率
When analyzing the human sperm chromosomes of the control group by using the heterologous fertilization system, it was found that the chromosome aberration rate was high (6.2% ~ 13.0%) and these aberrations may be caused by human. Because, when using the same fertilization technique to analyze sperm from other species, the aberration rate is low, with a Chinese hamster sperm aberration rate of 1.3% and a mouse gain of 0.6%. Moreover, among human spontaneous abortions, the chromosomal aberrations are far less than the number of aberrations (94% of the aberrations are number distortions, only 3 to 6% are structural distortions and only half are considered new events Rearrangement). However, differences in sperm chromosome aberration rates between individuals and relative time stability in the same individual, and the use of known mutagens, the aberration rate