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1 临床资料 患者,男,19岁,学生,1998年11月5日14:00在学校卫生室由校医于左上臂三角肌常规皮肤消毒后,用一次性注射器肌肉注射双价出血热疫苗1ml。该疫苗系杭州天元生物药业公司生产,批号980601,效期991128。患者于接种后1小时出现耳鸣,似火车轰鸣声,随到校医处求治,按偶合感冒给予速效感冒片2片、龙胆泻肝丸10粒,口服,每日3次。患者同班的其他学生未出现任何不适。11月6日10:00,患者到区防疫站接种门诊求治,主述耳鸣加重。门诊医生体检:患者一般情况好,体温36.8℃,排除感冒和双耳器质性病变。经询问患者既往有磺胺药过敏史,门诊医生给予扑尔敏4mg,地塞米松5mg,VitC0.1g、VitB_110mg,口服,每日3次。以后连续7天随访,第4天症状减轻,第6天症状消失。
1 Clinical data Patients, male, 19 years old, student, November 5, 1998 14:00 In the school health room by the school doctor in the left upper arm deltoid skin routine disinfection, with a single syringe intramuscular injection of bivalent hemorrhagic fever vaccine 1ml. The vaccine Department of Hangzhou Tianyuan bio-pharmaceutical company production, batch number 980601, the validity of 991,128. Patients tinnitus 1 hour after inoculation, it seems the roar of the train, with the school doctor for treatment, according to the flu to give quick cold tablets 2 tablets, 10 tablets of Longdanxiegan, oral, 3 times a day. Other students in their class did not experience any discomfort. At 10:00 on the 6th of November, the patient went to the district epidemic prevention station to inoculate the clinic for treatment, and the chief narrative tinnitus was aggravated. Outpatient medical examination: Patients generally good, body temperature 36.8 ℃, excluding cold and ear organic disease. After asking patients with past history of allergy to sulfa drugs, clinic doctors give chlorpheniramine 4mg, dexamethasone 5mg, VitC0.1g, VitB_110mg, orally, 3 times a day. Follow-up for 7 consecutive days, the first 4 days to alleviate the symptoms, the first 6 days the symptoms disappear.