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目的探讨血液灌流抢救急性百草枯中毒的疗效和价值。方法急性百草枯中毒患者56例,其中常规治疗组27例(对照组),常规治疗基础上加血液灌流组29例(治疗组)。组间比较用χ2检验。结果28 d死亡率:治疗组51.72%(15/29);对照组88.89%(24/27),P<0.05。血液灌流起始时间对28 d死亡率影响:中毒6 h内者死亡率25%(5/20);中毒6 h后者死亡率77.78%(7/9),P<0.05。结论血液灌流抢救急性百草枯中毒疗效确切;早期进行效果更好。
Objective To investigate the efficacy and value of hemoperfusion for acute paraquat poisoning. Methods Acute paraquat poisoning in 56 patients, of which 27 cases of conventional treatment group (control group), on the basis of routine treatment plus hemoperfusion group 29 cases (treatment group). Comparison between groups using χ2 test. Results The 28-day mortality rate was 51.72% (15/29) in the treatment group and 88.89% (24/27) in the control group, P <0.05. The effect of initial time of hemoperfusion on 28-day mortality rate was 25% (5/20) after poisoning within 6 hours and 77.78% (7/9) after 6-hour poisoning, P <0.05. Conclusion Hemoperfusion is effective in treating acute paraquat poisoning and has a better effect in early stage.