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呋喃西林在临床的应用近年来日益广泛,由于用量过大或用药时间过长所产生的副作用的报告亦日见增加,对药物过敏而发生皮疹据文献报告约占1—6%。但尚未见有文献报告因对呋喃西林过敏而引起急性溶血性贫血并发血红蛋白尿的。我科于1962年4月曾在门诊遇到一冽,今报告如下:患儿曹×,男,18个月,河南人,汉族,门诊号7152—2,于1962年4月25日下午第一次门诊,主诉:尿如浓茶半天;患儿近三天来流清涕,稍咳,不思饮食,于就诊当天上午(?)在保健站就医,给予呋喃西林100mg 及匹拉米洞一片(全量分三次服),患儿于服药后无特殊表现,但在下午发现尿红色如浓茶样,量不多,无尿频尿痛和浮肿现象,无呕
Nitrofurantin has been widely used in clinical practice in recent years. The reports of side effects due to overdosage or overdosage have also been increasing day by day. According to the literature, nitrofurantoin is reported in about 1% to 6% of the cases. However, there have been no reports of acute hemolytic anemia associated with hemoglobinuria due to allergic reactions to nitrofurazone. In April 1962, our department met a doctor in the clinic. The report is as follows: Children × Cao, male, 18 months, Henan, Han nationality, outpatient number 7152-2, on the afternoon of April 25, 1962 An outpatient clinic, the main complaint: urine such as concentrated tea half a day; children runny nose in the past three days, a little cough, do not think diet, on the morning of the doctor’s day (?) Medical treatment at the health station, given nitrofurazone 100mg and Pami meters hole (Full dose of three servings), children with no special symptoms after taking the medication, but in the afternoon found urine red like thick tea, small amount, no dysuria and edema, no vomiting