狼疮性肾炎是系统性红斑狼疮(简称SLE)最常见且严重的内脏损害,其发生率为50～70％;亦常是导致患者死亡的原因之一。多数学者认为本病易发生在SLE的早期,约1/3的患者在肾小球系膜处发现有免疫复合物沉积时,而临床无肾炎的表现,因而,狼疮性肾炎的早期发现有时十分困难。本文就我院1957～1979年成人108例SLE患者中符合狼疮性肾炎的70例作分析,对其病因,临床分类及早期诊断等有关问题进行讨论。 Lupus nephritis is the most common and serious visceral damage of systemic lupus erythematosus (SLE), its incidence is 50 ~ 70%; is also often one of the reasons leading to death in patients. Most scholars believe that the disease is prone to early SLE, about 1/3 of patients found in glomerular mesangial immune complex deposition, and clinical manifestations of no nephritis, therefore, early detection of lupus nephritis is sometimes very difficult. In this paper, from 1957 to 1979 in our hospital, 108 cases of adult patients with lupus nephritis in 70 cases were analyzed, the etiology, clinical classification and early diagnosis and other related issues are discussed.