糖尿病足溃疡是糖尿病微循环病变常见的慢性并发症之一,其创面的治疗是临床上最为棘手的难题之一,封闭负压引流技术经过近十年的发展,在临床治疗糖尿病足溃疡中有较明显的疗效。但是封闭负压引流的机制还远没有揭示清楚,现将 Diabetic foot ulcer is one of the common chronic complications of diabetic microcirculation. Its wound treatment is one of the most difficult problems in clinical practice. After nearly 10 years of development of closed negative pressure drainage technology, there are More obvious effect. However, the mechanism of closure of negative pressure drainage is far from clear, now