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1966年 Bradley 等在半固体琼脂培养基中培养小鼠骨髓细胞成功后,体外造血细胞培养的方法不断改进。特别1979年以来,进展颇为迅速。不仅能使小鼠各种造血细胞亚群在体外培养基中长成集落,且某些方法已用于培养人的造血细胞。这对于研究血细胞的发生及调节机理,探讨各种造血功能障碍的病因和细胞缺陷提供了途径。临床上也正在广泛应用于许多疾病的早期诊断、指导治疗和判断预后等。
In 1966 Bradley and other semi-solid agar medium in cultured mouse bone marrow cells after the success of in vitro hematopoietic cell culture methods continue to improve. In particular, progress has been rapid since 1979. Not only can make a variety of mouse hematopoietic cell subpopulations grow in vitro culture colonies, and some methods have been used to culture human hematopoietic cells. This is for the study of the occurrence and regulation of blood cells to explore the causes of various hematopoietic disorders and cell defects provide a way. Clinically, it is also widely used in many diseases early diagnosis, treatment and prognosis.