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微血管密度(Microvessel.Density简称MVD)测定,与子宫宫颈癌预后有一定关系,据文献报导MVD≤20/每视野有94％左右患者可以存活5年以上,而MVD>20/每视野仅有29％左右患者存活。通过对肿瘤组织标本测定微血管密度,可预测肿瘤复发、转归,并对手术后治疗等都有一定指导意义。而宫颈癌的预后又与临床分期直接相关。本研究利用免疫组化方法对20例病理诊断为宫颈癌标本做了MVD测定临床分期相关性比较,现将方法报告如下: 1、材料与方法:
Microvessel density (Microvessel.Density referred to as MVD) determination and prognosis of uterine cervical cancer have a certain relationship, according to the literature reported MVD≤20 / per field of vision about 94% of patients can survive more than 5 years, and MVD> 20 / per field of vision is only 29 % Survival of patients. Tumor tissue samples through the determination of microvessel density, tumor recurrence can be predicted, prognosis, and postoperative treatment have some guiding significance. The prognosis of cervical cancer is directly related to clinical stage. In this study, immunohistochemical method for pathological diagnosis of 20 cases of cervical cancer MVD determination of clinical stage correlation, the method is reported as follows: 1, materials and methods: