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本文对30例正常未孕妇女,33例正常足月妊娠孕妇及28例妊高征孕妇采用双抗体PEG法测定血清T_3、T_4、TSH浓度,结果表明正常足月妊娠孕妇血清T_3浓度较正常未孕妇女显著增高(P<0.001),妊高征孕妇血清T_3浓度较正常孕妇显著降低(P<0.001),妊高征孕妇血清TSH浓度较正常孕妇显著增高(P<0.001),三组妇女血清T_4浓度差异不显著。同时妊高征妇女分娩小于胎龄儿者低T_3综合征发生率明显增高(P<0.05);轻、中度与重度妊高征孕妇血清T_4、T_3、TSH浓度比较无显著差异。提示妊高征孕妇甲状腺功能发生变化,推测妊高征孕妇IUGR及胎儿宫内窘迫发生率与血清T_3及TSH浓度有一定关系。
In this paper, the serum T_3, T_4 and TSH levels in 30 normal pregnant women, 33 normal pregnant women and 28 pregnant women with PIH were measured by double antibody PEG method. The results showed that serum T_3 concentrations in normal term pregnant women were higher than those in normal pregnant women The serum levels of T_3 in pregnant women with PIH were significantly lower than those in normal pregnant women (P <0.001), and the levels of serum TSH in pregnant women with PIH were significantly higher than those in normal pregnant women (P <0.001) T_4 concentration difference was not significant. The incidence of low T 3 syndrome in women with gestational hypertension during childbirth was significantly higher than that in children with gestational hypertension (P <0.05). There was no significant difference in serum T 4, T 3, and TSH levels among pregnant women with mild, moderate and severe PIH. Suggesting that pregnancy-induced hypertension pregnancy thyroid function changes, speculated that PIH pregnant women IUGR and fetal distress rates and serum T_3 and TSH concentrations have a certain relationship.