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为防治松材线虫病，１９８８－１９９２年间，使用３种药剂对松材线虫（Ｂｕｒｓａｐｈｅｌｅｎｃｈｕｓｘｙｌｏｐｈｉｌｕｓ）进行室内毒性测定，并选用５％克线磷颗粒剂在林间、盆栽树苗上作防治试验．巴丹在１００×１０－６时，线虫仍可存活、繁殖；Ｆ—００１药剂在５０×１０－６以上时，灭虫率均可达９０％以上，克线磷浓度在６０×１０－６以上时，则可完全抑制线虫的生长繁殖．在林间，以克线磷处理的黑松（Ｐｉｎｕｓｔｈｕｎｂｅｒｇｉｉ）植株，均比对照株死亡率低．盆栽苗上的施药、接种试验，更进一步证实了该药剂的防病效果．
In order to prevent and control pine wilt disease, three kinds of agents were used to determine the indoor toxicity of Bursaphelenchus xylophilus in 1988-1992, and five percent of the granules were used to prevent and control pine wood nematode. The nematodes could still survive and reproduce at the dosage of 100 × 10-6, while the insecticidal rates of F-001 could reach more than 90% when the dosage of F-001 was above 50 × 10-6. Above, it can completely inhibit the growth and reproduction of nematodes. In the forest, the Pinus thunbergii plants treated with cinnamate had lower mortality than the control plants. Potted seedlings on the application, vaccination test, and further confirmed the preventive effect of the agent.