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雷诺氏现象(RP)的特征是发作性指端缺血。典型发作过程包括指(趾)端依次出现界限清楚的苍白、青紫和发红三联症。一次发作时间自数分钟至几小时。诱发因素与暴露于寒冷或精神刺激有关。RP可分为原发性和继发性二类。前者原因不明,称为雷诺氏病;后者继发于全身性疾病或神经血管异常,与某些结缔组织病的关系尤为密切,常为这些疾病的先兆症状,经久不愈。RP 的发病机理不明。迄今没有满意的治疗方法。近两年来,我院应用心痛定Nifedipine)治疗 RP 患者14例,疗效明显,副作用小。现将初步观察结果作如下介绍。
Raynaud’s phenomenon (RP) is characterized by episodic finger ischemia. Typical episodes include the well-defined triptych, cyanosis and trimester trimester in turn at the digit. A time of attack from a few minutes to several hours. Induced by exposure to cold or mental stimulation. RP can be divided into two types of primary and secondary. The former cause is unknown, known as Raynaud’s disease; the latter secondary to systemic disease or neurovascular abnormalities, and some connective tissue disease is particularly closely related, often the aura symptoms of these diseases, prolonged unhealed. The pathogenesis of RP is unknown. So far no satisfactory treatment. The past two years, our hospital application of nifedipine Nifedipine) treatment of RP patients in 14 cases, the effect is obvious, side effects. The preliminary observations are as follows.