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采用随访观察的研究方法，观察了１３名感染ＨＣＶ的母亲和她们生的１５例婴儿的母婴传播ＨＣＶ可能性、传播机率和后果。１５例婴儿中，ＨＣＶ感染率为８６．７％，其中临床型１例（７．７％），亚临床型ＨＣ３例（２３．１％），隐性感染９例（６９．２％）。抗－ＨＣＶ阳性率为：３月龄前为１００．０％，６月龄开始有阴转，１８月龄降至３３．３％，到３６个月龄时仍有１例阳性（１６．７％）。ＨＣＶＲＮＡ检出率：９月龄前与抗－ＨＣＶ相同，之后较高，１８月龄后为６６．７％，３６月龄时为３３．３％。婴儿感染ＨＣＶ的临床类型与母亲怀孕时的病态有关，母亲孕期为临床型ＨＣ者，其婴儿易发展为临床型或亚临床型感染；ＨＣＶＲＮＡ和抗－ＨＣＶ持续时间也相对长。ＨＣＶ感染婴儿可能均为宫内感染，而非出生后所致。母亲及其婴儿血清标本ＨＣＶＲＮＡ基因型均为Ⅱ型。
A follow-up study was conducted to determine the probability of mother-to-child transmission of HCV, the probability of transmission and the consequences of 13 mothers infected with HCV and 15 infants born to them. In 15 infants, the HCV infection rate was 86.7%, of which 1 was clinical (7.7%), 3 (23.1%) subclinical HC and 9 (69.2%) were latent infection. The anti-HCV positive rate was 100.0% at 3 months of age, with a negative turn at 6 months and 33.3% at 18 months, and still one case at 36 months (16.7 %). HCV RNA detection rate: 9 months ago with anti-HCV the same, then higher, 66.7% after 18 months, 33.3% at 36 months of age. The clinical type of HCV infection in infants is related to the morbidity of the mother during pregnancy. The mother is a clinical HC in her pregnancy, and her infant tends to develop clinical or subclinical infection. The HCV RNA and anti-HCV duration are also relatively long. Infants infected with HCV may be intrauterine infection, not after birth. The HCVRNA genotypes of the serum samples from mothers and their infants were type Ⅱ.