本文叙述用作肝脏闪烁显影的~(113m)In胶体质量控制的一种简便、快速纸层析方法,常规地用于测定放射化学杂质,可以替代实验动物的器官分布研究或其它更费时间的方法(如电泳)。方法的原理是放射化学杂质(离子状态的铟)与EDTA螯合,这复合物用常规的甲醇溶液洗脱剂的纸层析易与胶体相分离。 This article describes a simple, rapid paper chromatography method for the ~ (113m) In colloidal quality control of hepatic scintigraphy that is routinely used for the determination of radiochemical impurities and may be used as an alternative to the study of organ distribution in laboratory animals or other time-consuming Method (such as electrophoresis). The principle of the method is the chelation of the radiochemical impurities (indium in the ionic state) with EDTA, which is easily phase separated from the colloids by paper chromatography using a conventional methanolic solution eluent.