本病是一种侵犯软骨为主的全身性非特异性炎性疾病。最近曾遇一例。兹报告如下: 男,35岁,因反复发热、关节痛5年,鞍鼻3年,加重半年,于1980年9月9日第5次就诊。患者于5年前突然出现发热、头痛、全身关节呈游走性疼痛、鼻塞、重听、皮肤起红色丘疹,无痒痛。当地医院诊断为“风湿热”。经用解热止痛剂、肾上腺皮质激素等药物治疗,曾一度缓解。近4年来经常有鼻红、肿、热、痛,伴鼻衄,流黄涕,外鼻渐塌陷,双眼外突伴疼痛、发红,咽喉疼痛及声音嘶哑。1年前右耳曾有红、热、痛,继而局部起硬结。近半年四肢麻木、疼痛、无力、肌肉逐渐萎缩,左手不能握拳。发作时用肾上腺皮质激素有效。体检:体温37℃。血压175/120。颅神经阴性。浅在淋巴结朱扪及。心肺正常。腹软,肝脾未扪及。四肢皮肤见色素沉着、活动好、肌肉萎缩,以左上肢 The disease is a violation of cartilage-based systemic non-specific inflammatory diseases. Recently encountered a case. It is hereby reported as follows: Male, 35 years old, suffering from recurrent fever, arthralgia for 5 years, saddle nose for 3 years and exacerbated for half a year and treated for the 5th time on September 9, 1980. 5 years ago, patients suddenly had fever, headache, migraine pain in systemic joints, nasal obstruction, severe hearing, the skin red papules, no itching pain. Local hospital diagnosed as “rheumatic fever.” After using antipyretic analgesics, adrenal cortex hormones and other drugs, once relieved. In recent 4 years, there are often nose red, swollen, hot, painful, accompanied by epistaxis, runny nose, nasal subsidence, bilateral extraocular pain, redness, sore throat and hoarseness. A year ago, the right ear had red, hot, pain, and then from the partial induration. Nearly six months numbness, pain, weakness, muscle gradually shrinking, left hand can not make a fist. Attack with adrenal cortex hormones effective. Physical examination: body temperature 37 ℃. Blood pressure 175/120. Cranial nerve is negative. Shallow in the lymph nodes Zhu palpable. Cardiopulmonary normal. Abdomen soft, liver and spleen not palpable. Pigmentation of limb skin, activity, muscle atrophy to the left upper limb