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用单克隆抗体MC5对经福尔马林固定的113例大肠腺瘤组织切片进行免疫组化PAP法检测。结果显示MC5相应抗原的表达阳性率分别为:伴有癌变的腺瘤83.87％、伴有异形增生的腺瘤54.76％、腺瘤45％,其阳性率比较差异有非常显著性(P<0.01)。
113 cases of colorectal adenoma tissue sections fixed with formalin were detected by immunohistochemistry PAP with monoclonal antibody MC5. The positive rates of MC5 antigen expression were 83.87% with adenocarcinoma, 54.76% with adenomatous adenoma and 45% with adenoma, respectively. The positive rate of MC5 was significantly different (P <0.01) .