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在德国妇女中,恶性肠道肿瘤仅次于乳腺癌占第二位,且主要发生在围绝经期和绝经后妇女,故恶性肠肿瘤患者是否可用性激素替代是妇科医师所面临的日益常见问题。1989～1997年,对52例结肠及直肠恶性肿瘤治疗结束后的患者进行替代治疗,42例结肠癌、10例直肠癌手术治疗达临床治愈。考虑适当的激素替代的有利作用,对于有益更年期机能缺失症状和对结肠直肠恶性肿瘤长期缺乏雌激素的预防,从相同环境中选择相同年龄既无恶性肿瘤、又无激素替代的478例妇女作对照。结肠直肠癌患
Among German women, the number of malignant intestinal tumors is second only to that of breast cancer, and mainly occurs in perimenopausal and postmenopausal women. Therefore, the availability of sex hormone replacement in patients with malignant intestinal tumors is an increasingly common problem faced by gynecologists. From 1989 to 1997, 52 cases of colon and rectal malignancies were treated with replacement therapy, 42 cases of colon cancer, 10 cases of rectal cancer surgery for clinical cure. Considering the beneficial effects of appropriate hormone replacement, 478 women of the same age who had neither malignant tumors nor hormone replacement were selected from the same setting for the benefit of beneficial menopausal symptoms and long-term lack of estrogen for colorectal malignancies . Colorectal cancer