用胺碘酮治疗可出现各种心脏外副作用。在长期服用胺碘酮的患者中,15～40％可出现无症状性肝功能损害,一般血清转氨酶浓度升高至正常的1.5～4倍。作者报告2例静注胺碘酮24小时后发生急性肝炎。例1:女性,48岁,有二尖瓣及主动脉瓣置换史,入院时有慢性心功能不全及快速房颤(心室率140～180次/分),肝脏酶血清浓度正常,天门冬氨 With amiodarone treatment can occur a variety of extra-cardiac side effects. In long-term use of amiodarone in patients, 15 to 40% of asymptomatic liver dysfunction can occur, the general serum aminotransferase concentration increased to 1.5 to 4 times normal. The authors report two cases of acute amiodarone intravenously after 24 hours of acute hepatitis. Example 1: Female, age 48, with mitral valve and aortic valve replacement history, admission to chronic heart failure and rapid atrial fibrillation (ventricular rate 140 to 180 beats / min), liver enzyme serum normal, aspartate ammonia