目的　探讨基底细胞癌的病理生物学行为与临床治疗的相关性。方法　对 136例基底细胞癌病例 ,根据其病理生物学行为及病变部位和范围 ,采取扩大切除后单纯缝合 ,局部皮瓣修复 ,植皮及Mohs手术方法进行临床治疗。结果　 136例病例全部Ⅰ期愈合 ,经 2～ 9年随访 ,效果满意 ,无 1例复发。结论　认识到这类恶性肿瘤的特点是病变较为局限 ,恶性程度低 ,具有多种病理分型 ,极少发生转移 ,又多发于面中部 ,对人的容貌影响较大 ,所以基底细胞癌的治疗必须结合临床病理分型区别对待。早期手术切除 ,重视病变切除范围 ,选择适当的方法修复创面 ,有助于本病的彻底治疗 Objective To investigate the correlation between pathological biological behavior and clinical treatment of basal cell carcinoma. Methods A total of 136 cases of basal cell carcinoma were treated with simple suture, partial flap repair, skin grafting and Mohs surgery according to their pathological biological behavior and lesion location and extent. Results All 136 cases were healed by phase I. After 2 to 9 years of follow-up, the results were satisfactory. No recurrence occurred. Conclusion It is recognized that this type of malignant tumor is characterized by relatively limited lesions, low degree of malignancy, multiple pathological types, very few metastases, and multiple facial lesions, which have a great influence on the appearance of humans. Therefore, the treatment of basal cell carcinoma Must be combined with the clinical pathological classification treatment. Early surgical resection, the importance of resection of the lesion, and the choice of appropriate methods to repair the wound will help the treatment of the disease