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染色体脆性部位与白血病之间的关系日益引起人们的重视,染色体脆性部位可能是染色体结构重排的诱因,染色体结构重排又可激活癌基因而导致白血病的发生。本文报告20例急性非淋巴细胞白血病(ANLL)患者外周血染色体畸变率及常见型脆性部位的结果。1 对象与方法1.1 对象20例均为?
The relationship between chromosomal fragile sites and leukemia has attracted increasing attention. Chromosomal fragile sites may be the cause of chromosomal rearrangements. Chromosome rearrangements can also activate oncogenes and lead to the development of leukemia. This article reports the results of peripheral blood chromosome aberrations and common brittle sites in 20 patients with acute nonlymphocytic leukemia (ANLL). 1 objects and methods 1.1 object 20 cases are?