论文部分内容阅读
目的分析成都地区中老年居民脉压(pulse pressure,PP)及脉压指数(pulse presure index,PPI)与高尿酸血症(hyperuricemia,HUA)的关系。方法利用2007年5月代谢综合征研究调查资料(共1 061人),依据PP[≤60mm Hg(1mm Hg=0.133kPa)、>60mm Hg]和PPI(≤0.450、>0.450)将人群分为正常组及增高组,分析两组人群尿酸水平及HUA患病率,采用单因素回归及logistic回归分析PP及PPI与HUA关系。结果①PP/PPI增高组血浆尿酸水平明显高于PP/PPI正常组,差异有统计学意义(P=0.000)。②PP/PPI增高组HUA患病率明显高于PP/PPI正常组,差异有统计学意义(P=0.026、0.027)。③单因素回归和logistic回归分析皆提示PP及PPI与HUA呈正相关。结论成都地区PP及PPI与血浆尿酸水平关系密切,PP/PPI增高可能是HUA的危险因素。
Objective To analyze the relationship between pulse pressure (PP) and pulse presure index (PPI) and hyperuricemia (HUA) among middle-aged and elderly residents in Chengdu. Methods According to the data of May 2007 Metabolic Syndrome Survey (1 061), the population was divided into PPI (≤0.60mm Hg) and PPI (≤0.450,> 0.450) according to PP [≤60mm Hg Normal group and high group. The level of uric acid and prevalence of HUA in both groups were analyzed. The relationship between PP and PPI and HUA was analyzed by univariate regression and logistic regression. Results ① The level of plasma uric acid in PP / PPI group was significantly higher than that in PP / PPI group (P = 0.000). ② The prevalence of HUA in PP / PPI increased group was significantly higher than that in PP / PPI normal group, the difference was statistically significant (P = 0.026,0.027). ③ Univariate regression analysis and logistic regression analysis indicated that PP and PPI were positively correlated with HUA. Conclusion The PP and PPI in Chengdu are closely related to the level of plasma uric acid. Increasing PP / PPI may be the risk factor for HUA.