论文部分内容阅读
本文报告一例伴发胸膜间皮瘤的多中心性网织组织细胞增生病,用环磷酰胺治疗获缓解.病例男性,72岁,病史3个月.开始在右手背面第一掌指关节出现一小结节,随后在双手及耳廓出现更多结节.双手,上臂部及面部出现无症状红斑,双手疼痛并有强直和功能障碍.从上背部红斑处取皮肤活检,显示在真皮中层有胞浆呈毛玻璃样的,较大的组织细胞及多核细胞弥漫聚集,后者胞浆PAS染色强阳性.右膝滑膜活检几乎均由不同表现的组织细胞组成,伴有一些双核、偶见多核的细胞.滑膜液混浊,55%为淋巴细胞,36%为单核细
This article reports a case of pleural mesothelioma multicentric reticulocyte proliferative disease, with cyclophosphamide treatment was relieved.Patients male, 72 years old, history of 3 months.Started in the first right hand back of the first metacarpophalangeal joint appears Small nodules, followed by more nodules in both hands and pinna, asymptomatic erythema on both hands, upper arm and face, pain in both hands and rigidity and dysfunction, skin biopsy taken from upper back erythema, The cytoplasm was stained glassy, large tissue cells and multinucleated cells diffusely gathered, which was strongly positive cytoplasmic PAS staining.The right knee synovial biopsy almost all by the different performance of the tissue cells, accompanied by some dual-core, occasionally multi-core Of the synovial fluid cloudy, 55% of lymphocytes, monocytes 36%