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治疗以新方法使用老药氯霉素和甲砜霉素甲砜霉素为氯霉素的同系物,乃以甲磺酰基置换了氯霉素的硝基而成。本品同氯霉素一样,能产生可逆的骨髓抑制,然而由于其没有硝基,因而能防止引起自发性再生障碍性贫血。甲砜霉素的抗菌谱和氯霉素相似。曾比较了临床上最常见的有致病性的厌氧菌对甲砜霉素和氯霉素的敏感性。结果显示,487株厌氧菌中96%的菌株对8mg/L 或更低浓度的氯霉素敏感,261株厌氧菌中92%的菌株对与氯霉素同样浓度的甲砜霉素敏感;在16mg/L 时,两者均能抑制99%的受试菌,所以实际上氯霉素和
Treatment with a new method using the old drug chloramphenicol and thiamphenicol thiamphenicol chloramphenicol homologue, is substituted with methanesulfonyl chloramphenicol nitro made. This product, like chloramphenicol, produces reversible myelosuppression. However, due to its lack of nitro group, it prevents spontaneous aplastic anemia. Thiamphenicol antimicrobial spectrum and chloramphenicol similar. Have compared the most common pathogenic anaerobic bacteria on thiamphenicol and chloramphenicol sensitivity. The results showed that 96% of 487 anaerobic strains were sensitive to chloramphenicol at a concentration of 8 mg / L or lower, and 92% of 261 anaerobic strains were sensitive to thiamphenicol at the same concentration as chloramphenicol ; At 16mg / L, both can inhibit 99% of the tested bacteria, so in fact chloramphenicol and