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三维适形放射治疗(3D-CRT)可以改进描画靶区体积等剂量线的能力,可以选择射束角度,得到更精确的剂量分布,成为非小细胞肺癌病人(NSCLC)治疗重要进展的代表。该研究分析采用3D-CRT的NSCLC的长期结果,确定与采用该技术相关的特定预后因子。 选择1991年3月-1998年12月间207例不能手术的NSCLC病例进行 3D-CRT。肿瘤的直径为 1～11cm,由CT数据决定的大体肿瘤体积(GTV)范围为2～759cm~3,计划靶体积(PTV)从21～1095 cm~3。使用三维放射治疗计划系统(3D-RTP)。进行整个胸部和上腹部CT扫描,未行呼吸控制。采用北卡罗莱那州大学计算机小组开发的软件描绘GTV,临床靶区
Three-dimensional conformal radiotherapy (3D-CRT) can improve the ability to draw isodose volumes of target volumes, select beam angles for more accurate dose distribution, and represent a significant advance in the treatment of patients with non-small cell lung cancer (NSCLC). The study analyzed the long-term outcome of 3D-CRT-based NSCLC to determine the specific prognostic factors associated with using this technique. A total of 207 patients with unresectable NSCLC were selected for 3D-CRT from March 1991 to December 1998. The diameter of the tumor ranged from 1 to 11 cm. The gross tumor volume (GTV) ranged from 2 to 759 cm -3 as determined by CT data and the planned target volume (PTV) ranged from 21 to 1095 cm -3. Using a three-dimensional radiotherapy planning system (3D-RTP). The entire chest and upper abdomen CT scan, no breathing control. Software developed by the North Carolina State University Computer Group depict GTV, a clinical target