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对近30年芫花甘草同方配伍的文献进行了回顾性调查与分析,并对基层医院近3年78 238首处方调查。发现芫花甘草配伍临床应用少,实验研究多。文献报导仅有坠胎、冻疮、哮喘3种疾病,基层调研仅有3首处方。实验研究从最早的观察临床症状体征到细胞色素酶与液相色谱,研究逐渐深入。十八反药物配伍研究可以从古代文献数据挖掘与现代实验研究相结合,并借鉴其他反药的研究方法,为临床安全用药提供依据。
The literature about the compatibility of Daphne genkwa with the same side in the past 30 years was retrospectively investigated and analyzed, and 78 238 prescriptions were surveyed in primary hospitals in the recent 3 years. Found compatibility of clinical medicine licorice less, experimental study and more. Reported only the abortion, chilblains, asthma three kinds of diseases, grassroots research has only three prescriptions. Experimental study From the earliest observation of clinical signs and symptoms to cytochrome enzyme and liquid chromatography, the research gradually. Eighteen anti-drug compatibility research from the ancient literature data mining and modern experimental research combined with other anti-drug research methods, to provide the basis for clinical safety medication.