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本文总结我院从1977年1月至1981年12月;抢救口服大量异烟肼50例,现介绍如下:临床资料本组50例(占内科住院病人10.9％)均为一次口服大量异烟肼药物,剂量为5～30克。最小年龄6岁,最大年龄57岁。以16～25岁为最多33例占66％。6～15岁3例6％。26岁～57岁14例占28％。男性13例,女性37例;男∶女≈1∶3。从口服药物到症状出现时间为0.5～1.5小时。在1小时内发病占80％。从服药到医院抢救三小时以内者40例占80％。超过4小时8例占16％。超过15小时的2例占4％。死亡4例占8％。临床表现如下表,50例均出现抽搐现象,可由阵发性肌颤动以致惊厥。在抽搐时均伴有发绀;伴有双眼向外上方斜视者
This article summarizes our hospital from January 1977 to December 1981; rescue a large amount of 50 cases of oral isoniazid, are described below: Clinical data of the group of 50 patients (accounting for 10.9% of inpatient medical inpatient) were a large oral administration of isoniazid Drugs, doses of 5 to 30 grams. The youngest is 6 years old and the oldest is 57 years old. To 16 to 25 years old up to 33 cases accounted for 66%. 6 ~ 15 years old in 3 cases 6%. 26 years old to 57 years old 14 cases accounted for 28%. 13 males and 37 females; males: females ≈ 1: 3. From oral drugs to symptoms appear time is 0.5 to 1.5 hours. In 1 hour accounted for 80% of the disease. From taking medicine to the hospital within three hours of rescue 40 cases accounted for 80%. More than 4 hours 8 cases accounted for 16%. Two cases accounted for 4% over 15 hours. 4 cases died of 8%. Clinical manifestations in the following table, 50 cases were convulsions, may be caused by paroxysmal muscle fibrillation convulsions. Convulsions are accompanied by cyanosis; accompanied by both eyes outward strabismus above