在热带非洲常用氯喹单剂治疗疟疾,对减少发病和死亡有较好效果。本文作者对剂量、疗效及药物反应作了进一步观察。选择尼日利亚北部有1,935人的3个居民点为试点。当地儿童的原虫率在60%左右,其中恶性疟占97%,此外为三日疟和卵形疟。将血检疟原虫阳性的对象分为4组,按表列剂量 Chloroquine, a commonly used single-dose treatment of malaria in tropical Africa, is effective in reducing morbidity and mortality. The authors of the dose, efficacy and drug reactions were further observed. Three settlements of 1,935 people in northern Nigeria were selected as pilot sites. The protozoal rate of local children is about 60%, of which 97% of falciparum malaria, in addition to three days of malaria and oval malaria. The blood test positive for Plasmodium were divided into 4 groups, according to the listed dose