目的：研究低剂量电离辐射能否诱导免疫适应性反应。方法：采用单克隆抗体免疫荧光标记技术，流式细胞术检测 Ｔ Ｃ Ｒ／ Ｃ Ｄ３ 受体。采用３ Ｈ Ｔｄ Ｒ 掺入法测定胸腺细胞自发增殖率及丝裂原诱导的脾细胞增殖率。采用 Ｃ Ｔ Ｌ Ｌ 依赖株检测 Ｉ Ｌ２ 活性。结果：证明免疫适应性反应的最佳诱导剂量为００２５～０１ Ｇｙ，最佳攻击剂量为１０～１５ Ｇｙ，最佳诱导时间为６～１２ ｈ。结论：低剂量辐射能诱导免疫适应性反应。 Objective: To investigate whether low-dose ionizing radiation can induce immune adaptive response. Methods: Monoclonal antibody immunofluorescence labeling was used to detect T C R / C D3 receptors by flow cytometry. The 3H-TdR incorporation method was used to determine the rate of spontaneous proliferation of thymus cells and the rate of proliferation induced by mitogen. C T L L-dependent strains were used to detect I L 2 activity. Results: The optimal induction dose for immune adaptive response was 0025 ~ 01 Gy. The optimal challenge dose was 10 ~ 15 Gy and the optimal induction time was 6 ~ 12 h. Conclusion: Low dose radiation can induce immune adaptive response.