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本实验观察了扶正升白胶囊对白细胞减少小鼠脾细胞增殖、白细胞介素Ⅱ（ＩＬ－２）活性、脂质过氧化物（ＬＰＯ）含量及雄性大鼠血清睾酮浓度的影响。结果表明，治疗组脾细胞增殖、ＩＬ－２活性、睾酮浓度明显高于对照组（Ｐ＜０．０５～０．０１），ＬＰＯ略有降低，但无统计学意义。其白细胞升高与ＬＰＯ含量无相关，与Ｔ淋巴细胞增殖及ＩＬ－２活性呈正相关。提示该方药升高白细胞的疗效机理可能与促进Ｔ淋巴细胞增殖、提高ＩＬ－２活性、提高睾酮浓度有关，与抗ＬＰＯ无关。
This experiment was conducted to observe the effect of Fuzheng Shengbai Capsule on spleen cell proliferation, interleukin-2 (IL-2) activity, lipid peroxide (LPO) content and serum testosterone concentration in male rats with leukopenia. The results showed that the spleen cell proliferation, IL-2 activity, and testosterone concentration in the treatment group were significantly higher than those in the control group (P<0.05-0.01), and the LPO was slightly decreased, but there was no statistical significance. There was no correlation between leukocytosis and LPO content, and there was a positive correlation between T lymphocyte proliferation and IL-2 activity. It is suggested that the therapeutic mechanism of this prescription for increasing leukocyte may be related to promoting the proliferation of T lymphocytes, increasing the activity of IL-2, increasing the concentration of testosterone, and not related to the anti-LPO.