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为研究用羊膜腔内注射利凡诺加服中药清宫汤对中期妊娠引产的效果,对治疗组120例和不加服清宫汤的对照组85例进行临床对比观察。结果治疗组和对照组的平均引产时间各为36小时和51小时(P<0.01);产后有胎盘胎膜残留的各为7.5％和83.53％(P<0.01);出血量少于平均月经量2倍的各为65％和37.65％(P<0.01);恶露干净时间短于8天的各为52.81％和20.75％,超过10天的各为3.37％和18.87％(P<0.01)。提示清宫汤配合利凡诺优于单用利凡诺治疗,能缩短引产时间,减少出血量、促进恶露干净。动物实验证明清宫汤能增强离体动情小鼠子宫平滑肌的收缩功能,增强收缩频率和活动力;并能减轻小鼠耳肿及腹腔内血管通透性异常,增强抗炎作用,与临床疗效相对应。
In order to study the effect of rivanol plus amikacin in induction of labor in the second trimester of pregnancy induced by amniotic injection, clinical observation was made on 120 cases in the treatment group and 85 cases in the control group without Qingong Decoction. Results The average induction of labor time was 36 hours and 51 hours (P <0.01) in the treatment group and the control group, 7.5% and 83.53% (P <0.01) in the placenta after birth, respectively. The amount of bleeding was less than the average menstrual flow 65.8% and 37.65% (P <0.01) for 2-fold and 52.81% and 20.75% respectively for clean spots less than 8 days and 3.37% and 18.87% respectively over 10 days (P <0.01). Prompt Qinglianguo rivanol better than rivanol treatment alone, can shorten the time of induction of labor, reduce the amount of bleeding, and promote clean. Animal experiments show that Qing Gong Tang can enhance the contractile function of uterine smooth muscle in isolated mouse with estrus and increase the frequency and activity of contraction; and can alleviate the mice ear and intraperitoneal vascular permeability abnormalities, enhance the anti-inflammatory effect, and clinical efficacy phase correspond.