历史性前瞻性队列调查方法可用于探讨疾病的死因,在职业流行病学中应用很广。但用这种方法进行剂量(或接触水平)-反应关系研究的报道并不多见,而且高,低剂量组的人年数计算方法对研究结果影响很大。这里举例介绍一种较为合理的人年数计算方法。 一、举例 假设有一个包括10名工人(用序号1至10表示)的队列,10名工人都是从1960年到某厂参加工作的,追访至1980年。这10名工人中,有2名(1和2)于 The historic prospective cohort study can be used to investigate the cause of death and is widely used in occupational epidemiology. However, there are few reports about the relationship of dose (or exposure level) -reaction with this method, and the method of calculating the number of years in high and low dose groups has a great influence on the research results. Here’s an example to introduce a more reasonable method of calculating the number of people. First, for example, suppose there is a queue of 10 workers (numbered 1 to 10). All 10 workers took part in a job from 1960 to a factory and were chased until 1980. Of the 10 workers, two (1 and 2) were on the list