引言将统计矩这一概念应用到药物动力学上来,实际上是于1979年由 Yamaoka 等和 Cutler同时提出的。在药物动力学中尤其是体内消除过程和吸收过程的时间的求算方面,统计矩的运用引入注目。本评论的目的是阐明这些概念,评述计算方法,扩大其应用。药物在体内的转运是一随机过程。单个分子在体内隔室的运行是受或然性所支配。这是 INTRODUCTION The concept of statistical moments applied to pharmacokinetics was actually proposed by Yamaoka et al. And Cutler in 1979. The use of statistical moments has drawn attention in the calculation of pharmacokinetics, especially in the in vivo elimination process and in the absorption process. The purpose of this commentary is to clarify these concepts, review computational methods, and expand their applications. Drug transport in the body is a random process. The operation of a single molecule in an in vivo compartment is governed by probability. this is