六十年代初期,我国在日本血吸虫病性肝硬化病例的尸检中,曾发现肾脏有以肾小球病变为主的病理损害。Andrade等(1968)最早描述曼氏血吸虫病与肾病的关系。近十年来,国外有关曼氏血吸虫病肾病临床免疫病理的研究报告甚多,对日本血吸虫病与埃及血吸虫病的肾脏免疫病理变化亦有不少研究。现分实验性动物模型与临床病理两方面加以综述。 In the early 1960s, in the autopsy of schistosomiasis cirrhosis in our country, we found that the kidneys had the pathological damage that predominated glomerular lesions. Andrade et al. (1968) first described the relationship between Schistosoma mansoni and nephropathy. In the recent ten years, there are many foreign reports on the clinical immunopathology of Schistosoma mansoni nephropathy. There are also many studies on the pathological changes of renal immunity in schistosomiasis japonica and schistosomiasis japonica. Now divided into experimental animal models and clinical pathology are reviewed.