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目的 探讨重症病毒性脑炎 (VE)患儿应激性高血糖 (SHG)和电解质紊乱与病情发展的关系 ,并探索重症VE患儿血糖及血清钾、钠、钙的变化及其相互关系。方法 对 1999年 10月至 2 0 0 1年 5月吉林大学第一医院 5 8例重症VE患儿进行血糖及血清钾、钠、钙动态检测 ,并以 2 0例轻症VE患儿为对照组进行比较。结果 重症VE患儿易于发生SHG、低钠血症 (HN)、低钾血症 (HK )、低钙血症 (HC)。血糖的升高 ,血钠、血钙的降低与VE患儿病情轻重关系密切 ,随VE进入恢复期 ,存活者上述指标逐渐恢复正常。结论 重症VE患儿存在应激损伤 ,机体的过度应激反应亦可引起血清电解质的改变 ,由此加重内环境紊乱 ,故控制过度应激反应、稳定内环境对重症VE患儿十分有利
Objective To investigate the relationship between stress hyperglycemia (SHG) and electrolyte imbalance and the progression of the disease in children with severe viral encephalitis (VE) and to explore the changes of blood glucose, serum potassium, sodium and calcium and its correlation in children with severe VE. Methods The blood glucose, serum potassium, sodium and calcium in 58 severe VE patients from the First Hospital of Jilin University from October 1999 to May 2001 were measured. Twenty patients with mild VE were used as control Group to compare. Results SHG, hyponatremia (HN), hypokalemia (HK) and hypocalcemia (HC) are easy to occur in children with severe VE. Elevated blood glucose, serum sodium, decreased serum calcium and VE severity of illness in children with close, with the VE into the recovery period, the survivors of the above indicators gradually returned to normal. Conclusions There is stress injury in severe VE children and the over-stress response of the body can cause changes of serum electrolytes, which aggravates the disturbance of internal environment. Therefore, controlling excessive stress reaction and stabilizing internal environment are very beneficial for children with severe VE