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目的 为了评价内镜局部注射化疗药物加微波治疗与单纯经内镜局部注射化疗药物治疗老年人食管癌疗效。方法 对66例失去手术指征的老年人食管癌进行局部注射化疗或加微波治疗以评价两者的疗效。该研究采用局部注射化疗组32例,局部注射化疗加微波治疗组34例。疗程结束后观察两组治疗效果。结果 局部注射化疗加微波治疗组近期有效率(76.5％)明显高于单纯局部注射化疗组(P<0.05),前者进食改善情况也明显高于后者(P<0.05),前者半年及1年生存率(61.8％及23.5％)也明显高于后者(34.4％及9.4％)(P<0.05)。结论 局部化疗药物注射加微波治疗方法优于单纯局部注射化疗药物,提示对老年人晚期食管癌的局部治疗应尽量采用加微波治疗的方法。
Objective To evaluate the efficacy of local injection of chemotherapeutic drugs plus microwave therapy and local injection of chemotherapy drugs alone to treat esophageal cancer in the elderly. Methods 66 patients with esophageal cancer who had no indication of surgery were treated with local injection chemotherapy or microwave therapy to evaluate their efficacy. In the study, 32 patients received local injection chemotherapy and 34 patients received local injection chemotherapy plus microwave therapy. The treatment effect was observed after the end of the treatment. Results The effective rate (76.5%) in the local injection chemotherapy plus microwave treatment group was significantly higher than that in the local injection chemotherapy group (P<0.05). The improvement of the former diet was also significantly higher than the latter (P<0.05). The former was six months and one year. The survival rate (61.8% and 23.5%) was also significantly higher than the latter (34.4% and 9.4%) (P<0.05). Conclusions Local chemotherapy injection plus microwave treatment is better than local injection of chemotherapy drugs, suggesting that local treatment of advanced esophageal cancer in the elderly should use microwave therapy.