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目的探讨同型血外周动静脉同步换血对不同病因所致高胆红素血症的疗效。方法对不同病因高胆红素血症患儿均采用同型血外周动静脉同步换血，换血前后行血常规、生化、胆红素、血培养等检查。结果不同病因的高胆红素血症患儿换血前后胆红素对比均有显著降低（Ｐ＜００１），总胆红素换出率分别是３７８２％、４５５２％和４８４１％，平均换出率是４２６２％。在体重、输入量和换出量无显著差异（Ｐ＞００５）的情况下，各组间总胆红素和间接胆红素换出率无显著差异（Ｐ＞００５）。结论采用同型血对不同病因所致的高胆红素血症换血效果相近；外周动静脉同步换血是简单、实用的方法，值得推广。
Objective To investigate the efficacy of simultaneous blood exchange of the same type of peripheral arterial and venous blood on hyperbilirubinemia caused by different etiologies. Methods The hyperbilirubinemia patients with different etiologies were treated with the same type of peripheral arteriovenous and venous blood transfusion, blood tests, biochemistry, bilirubin and blood culture before and after transfusion. Results The bilirubin levels in children with hyperbilirubinemia with different etiologies were significantly lower (P <001) and the total bilirubin efflux rates were 3782%, 4552% and 48% respectively 41%, the average exchange rate is 42 62%. There were no significant differences (P> 005) in total bilirubin and indirect bilirubin exchange rate among the groups with no significant differences in body weight, input and output (P> 005). Conclusions The same blood transfusions of hyperbilirubinemia caused by different etiologies are similar. The synchronized exchanging of peripheral arteriovenous vessels is a simple and practical method that is worth promoting.