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很多信号传导分子可以作为药物的筛选靶位,由此产生了信号传导药物的概念,信号传导药物的作用是恢复细胞内信号传导分子的表达或活性异常及其所参与的信号传导通路异常。一般来说,利用药物使一个失活的或活性较低的信号传导分子恢复活性远较抑制一个活性过高或表达水平过高的信
Many signal transduction molecules can be used as drug screening targets, resulting in the concept of signal transduction drugs. The role of signal transduction drugs is to restore the expression of intracellular signal transduction molecules or abnormal activity and signaling pathways involved in their abnormalities. In general, the use of drugs to restore activity of an inactive or less active signaling molecule is much more effective than inhibiting a signal that is hyperactive or overexpressed