肺炎衣原体是一种新发现的重要呼吸道病原微生物 ,与慢性阻塞性肺疾病 (COPD)的发生、发展关系尤为密切 ,COPD患者肺炎衣原体慢性感染的长期存在或反复感染以及诱发的混合感染 ,可能是COPD反复发作难于治愈的一个重要原因 ,对于急性发作期的重度COPD患者 ,特别是那些病情迁延对一般抗感染治疗疗效不佳者应加用大环内酯类或喹诺酮类抗生素 Chlamydia pneumoniae is a newly discovered important respiratory pathogenic microorganism, which is closely related with the occurrence and development of chronic obstructive pulmonary disease (COPD). Chronic infection with Chlamydia pneumoniae in chronic obstructive pulmonary disease (COPD) may be COPD recurrent difficult to cure an important reason for the acute exacerbation of severe COPD patients, especially those whose condition is refractory to general anti-infective therapy should be added macrolides or quinolone antibiotics