原发性闭角型青光眼的病因及其与遗传的关系,目前尚无一致看法,多数作者倾向于系多基因遗传,显性遗传家系很少见。本文报告二家系连续3代8人罹患,男与女之比为5∶3,符合Mendel氏常染色体显性遗传规律。家系1 先证者,女,53岁。因头昏、噁心、眼胀痛、发红,于1978年7月11日入院。检查:右眼视力0.03, The primary cause of angle-closure glaucoma and its relationship with the genetic, there is no consensus, most authors tend to be multi-gene hereditary, dominance gene family is rare. This article reports two families of three consecutive generations of 8 people suffering from, male to female ratio of 5: 3, in line with Mendel’s autosomal dominant genetic law. Family 1 proband, female, 53 years old. Due to dizziness, nausea, eye pain, redness, in July 11, 1978 admission. Check: right eye vision 0.03,