20世纪抗生素和疫苗的应用有效地控制了全球感染性疾病的流行 ,正在改变人类患疾病谱 ;但是 ,真正消灭的感染性疾病只有天花一种。抗生素耐药问题日益严重 ,使得我们对感染性疾病的治疗越来越困难 ,细菌感染性疾病 (如肺炎、脑膜炎和败血症 )仍然是威胁儿童健康的主要疾病。链? The application of antibiotics and vaccines in the twentieth century effectively controlled the spread of the global infectious disease and is changing the spectrum of human disease; however, the real eradication of infectious diseases is small. The growing problem of antibiotic resistance has made it increasingly difficult for us to treat infectious diseases, and bacterial infectious diseases such as pneumonia, meningitis and septicemia remain the major diseases that threaten children’s health. chain?