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目的:分析酒精性消化性溃疡给予兰索拉唑和抗生素联合治疗的临床效果。方法:抽选我院酒精性消化性溃疡患者70例,按照不同用药方法分为两个组别,其中对照组(奥美拉唑联合抗生素)、试验组(兰索拉唑联合抗生素)各35例。观察临床疗效,比较用药毒副作用。结果 :试验组治疗有效34例(97.1%),不良反应发生3例(8.6%);对照组治疗有效28例(80.0%),不良反应发生10例(28.6%);且治疗后试验组Hp清除率(94.3%)高于对照组(77.1%)。P<0.05,差异有统计学意义。结论 :针对酒精性消化性溃疡患者,兰索拉唑和抗生素联合用药疗效确切,能够提高Hp清除率、减少不良反应,是一种安全有效的治疗方法。
Objective: To analyze the clinical effect of combination therapy of lansoprazole and antibiotics on alcoholic peptic ulcer. Methods: Seventy patients with alcoholic peptic ulcer in our hospital were selected and divided into two groups according to different medication methods. The control group (combination of omeprazole and antibiotics) and the test group (combination of lansoprazole and antibiotics) example. Observe the clinical curative effect, compare the side effects of drug use. Results: The treatment group was treated effectively in 34 cases (97.1%) and adverse reactions in 3 cases (8.6%). The control group was treated effectively in 28 cases (80.0%) and adverse reactions in 10 cases (28.6% Clearance rate (94.3%) was higher than that of the control group (77.1%). P <0.05, the difference was statistically significant. Conclusion: For patients with alcoholic peptic ulcer, lansoprazole and antibiotics combined with the exact effect, can improve Hp clearance, reduce adverse reactions, is a safe and effective treatment.