1973年北京制药工业研究所研制成功新药升白新,学名为地菲林葡萄糖甙(DiphyllinGlycoside)。Rao等曾报道,具有相同甙元的地菲林二甲基木糖甙(Diphyllin 3,4,-o-dimethyl xyloside,亦名 Cleistanthin-A)有显著的升白细胞作用,但毒性较大,未见临床应用的报道。由于迄今对慢性苯中毒引起的白细胞减少症在临床上仍未找到疗效满意的药物,我们应用升白新对急性、亚慢性苯中毒所致白细胞减少症进行实验治疗,并观察它对正常动物的升白细胞作用,以确定其升白细胞的疗效。 In 1973, Beijing Institute of Pharmaceutical Industry successfully developed a new drug Bai Shixin, a scientific name for the Diphenhydryl glucoside (DiphyllinGlycoside). Rao et al. Reported that Diphyllin 3, 4, -o-dimethyl xyloside (also named Cleistanthin-A) had a marked leukocyte uptake effect with the same aglycone but no toxicity Clinical application of the report. Due to the so far on the leukopenia caused by chronic benzene poisoning clinically still not found a satisfactory effect of the drug, we use or new white acute hypoxic syndrome of leukopenia induced experimental treatment and observed its rise in normal animals The role of leukocytes to determine the efficacy of their leukocytes.