The thermochemical kinetics of the rare earth ternary complex Sm(Gly)4Im(ClO4)3*2H2O (Gly-glycine, Im-imidazole) reacting with microbes (escherichia coli, bacillus subilis, staphylococcus aureus) was studied by means of Calvet microcalorimeter. The rate constant k of microbe growth was calculated, and the inhibition effect of these complexes to microbes was compared.